منابع مشابه
Adenyl Cyclase in Fat Cells
Among several lipolytic hormones tested, adrenocorticotropin (ACTH), epinephrine, glucagon, thyroid-stimulating hormone, and luteinizing hormone stimulated adenyl cyclase activity in a plasma membrane-rich fraction, termed “ghosts,” isolated from rat fat cells. The effects given by various combinations of these hormones, at maximally stimulating concentrations, were not additive, indicating tha...
متن کاملAdenyl cyclase activity in human alveolar macrophages.
The inflammatory mediators PGE2, DC-PGI2 and histamine as well as the beta-adrenergic drugs isoprenaline and salbutamol increase intracellular cyclic AMP-concentrations whereas Platelet Activating Factor does not induce any change in adenyl cyclase activity of normal human alveolar macrophages. Functional H2-histaminergic and beta 2-adrenergic receptor-subtypes are coupled to macrophage adenyl ...
متن کاملDecreased myocardial adenyl cyclase activity in hypothyroidism.
It has been suggested that hypothyroidism may alter the responsiveness of the heart to sympathetic stimulation. To define more precisely the interrelationship between hypothyroidism and catecholamine responsiveness we: (a) studied the effects of norepinephrine and fluoride on the activation of adenyl cyclase in the particulate fraction of heart homogenates from euthyroid and hypothyroid cats; a...
متن کاملStudies on adenyl cyclase system in myocardium (Part I). Adenyl cyclase system in the hypertrophied and failing rabbit hearts.
Many reports state a marked reduction of catecholamine (CA) in cardiac tissue and an increased CA concentration of serum and urine in patients with congestive heart failure 1)-5). Thus, it is assumed that the function of the impared heart might be supported by the increased blood CA. It has been reported that the inotropic 6)-12) and chronotropic response 13)-16) of CA to the cardiovascular sys...
متن کاملAdenyl cyclase system and cerebral energy state.
The energy charge potential of the cerebral adenylate system, the cerebral lactate: pyruvate system, and the cerebral glycogen level were used to characterize the cerebral energy state of the brain. Cerebral adenyl cyclase activity and cyclic AMP concentrations were investigated to evaluate their possible influence on the regulatory processes in brain metabolism. These biochemical parameters we...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1973
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1973.tb08277.x